Study Of The Prevalence of Microalbuminuria In Patients of Essential Hypertension And its Correlation With The Severity of Hypertension and Left Ventricular Hypertrophy

Dr.Papaiah Nirmal Pudota

Volume : VIII, Issue : XI, November - 2019

Study Of The Prevalence of Microalbuminuria In Patients of Essential Hypertension And its Correlation With The Severity of Hypertension and Left Ventricular Hypertrophy

Dr. Papaiah Nirmal Pudota

Abstract :

Objective:To detect the prevalence of microalbuminuria in 100 hypertensive patients and the its association with LVH(left ventricular hypertrophy) and lipid profile Methods:we performed a prospective analysis study of 100 patients visiting Balaji medical college and hospital,Chennai.Inclusion criteria :Hypertensive patients with BP>140/90 mmhg and age more than 30 years.Exclusion criteria:Patients with renal disease,T2DM,Ischemic heart disease,CVA,pregnancy.microalbuminuria was measured using the dip stick test ,defined as having UAE in the range of 30-300mg/24h Results:100 patients were involved in the study fulfilling the criteria.30 out of 100 patients had microalbuminuria. 21 males out of 45 were found to have microalbuminuria and 9 out of 25 females were found to have Microalbuminuria.Serum levels of cholesterol,Triglycerides,and uric acid in patients with microalbuminuria were higher than the levels in those with normal UAE(urine albumin excretion),and HDL(high density lipid) levels in patients with MA(microalbuminuria)were lower than levels in patient with normal UAE.On performing ECHO in the study patients ,LVH is noted to be seen in 29 out of 100 patients ,out of which 22 (73.3%) of the patients had microalbuminuria,and in 71 patients without LVH ,8 had microalbuminuria.Study shows a high statistical significant correlation between Microalbuminuria and Left ventricular hypertrophy(p value <0.01). Conclusion Hypertension is one of the most common global diseases causing significant mortality and morbidity.Therefore proper screening and assessment is required to identify patients at risk. Microalbuminuria is a cause for generalized atherosclerosis and increased renal endothelial dysfuntion,it positively correlates with the end organ damage such as left ventricular hypertrophy .Hence it serves as a marker of cardiovascular risk along with other parameters such as BP,lipid profile and smoking. So, screening for microalbuminuria must be considered to be part of initial work up in every hypertensive patient.