STUDY OF LIPID PROFILE AND HEPATIC CHANGES IN ULTRASONOGRAPHY IN OBESE AND OVERWEIGHT INDIVIDUALS IN CENTRAL INDIA

Dr. Anshul Dudani; Dr. Vijan Rai; Dr. Manjula Gupta; Dr. Krishna Kumar Kawre

Volume : IX, Issue : IV, April - 2020

STUDY OF LIPID PROFILE AND HEPATIC CHANGES IN ULTRASONOGRAPHY IN OBESE AND OVERWEIGHT INDIVIDUALS IN CENTRAL INDIA

Dr. Anshul Dudani, Dr. Vijan Rai, Dr. Manjula Gupta, Dr. Krishna Kumar Kawre

Abstract :

Background-Current study is an attempt to study the lipid profile and hepatic changes in ultrasonography in overweight & obese individuals in central India. Methodology- This was a cross sectional study at tertiary care Hospital for a period of 1 year on all the overweight and obese individuals belonging to >18 years of age. All the selected participants were subjected to further investigation including routine investigations (Fasting glucose, CBP, RFT including serum protein, LFT), Lipid Profile, hepatitis B and C testing and Ultrasonography (Abdomen). The findings thus obtained were studied to see for the change/variation of lipid profile and hepatic changes in ultrasonographic in different grades of Obesity. Result-The present study was conducted on a total of 150 overweight and obese individuals with BMI ≥25kg/m2. The study observed statistically significant association of obesity with age, waist circumference and TC/HDL ratio (p<0.05) whereas no such association was observed with gender, body fat %, and other lipid profile parameters (p>0.05). Pearson correlation coefficient observed triglyceride (r=10.194, p=0.018), WC (r=0.367, p<0.001) and Body fat % had significant positive correlation with the grades of obesity. However, HDL (r=-0.247, p=0.002) was negatively corrected which means by increasing the grades of obesity, HDL decreases. No association was obtained between grades of obesity and USG finings. Grades of obesity has no effect on different grades of fatty liver (p>0.05). Conclusion-Lipid abnormalities are observed during all stages of the obesity. Variable changes have been in lipid profile observed amongst fatty liver patients diagnosed on ultrasound. Early diagnosis and treatment of fatty liver with abnormal lipids and abnormal anthropometric parameters can prevent from long-term complication of fatty liver and obesity.