Study of Histomorphological Spectrum of Breast Diseases in a Tertiary care centre of Mumbai

Dr. Mayura Phulpagar; Dr. Rakesh Shedge; Dr. Darshana Wakkar

Volume : VII, Issue : VI, June - 2018

Study of Histomorphological Spectrum of Breast Diseases in a Tertiary care centre of Mumbai

Dr. Mayura Phulpagar, Dr. Rakesh Shedge, Dr. Darshana Wakkar

Abstract :

Introduction

Breast Cancer is the most common cancer in women worldwide, comprising 16% of all female cancers.⁽¹⁾ In India, cancer of east has overtaken cancer of cervix. ⁽²⁾ The mortality rates for east cancer in India are high in comparision to its incidence rates. A poor survival may be largely explained by the lack of or limited access to the early detection services and treatment. ⁽³⁾

Objective

The present study endeavours to analyse histomorphology of various east diseases over a decade retrospectively as well as prospectively in all age groups at a tertiary care centre in Mumbai.

Materials & Methods

All the east tissue specimens received in surgical pathology section of the Pathology department over a 10 year 10 month period were included in this study. Retrospectively, the information and data from clinical records was collected and analysed. Prospectively received east tissue specimens were processed, stained and evaluated for histomorphology. Gross features and clinical data were also noted.

Results

Breast lesions constituted 1.66% of all the surgical pathology specimens over a period of 10 years 10 months. Majority of the tumors, 68.3% were benign. Fioadenomas was the commonest east lesion followed by carcinomas (31.7%). Inflammatory lesions were the second most common benign east lesions (10.3%). Gynaecomastia was the commonest east lesion in males. Carcinomas in our study presented at younger age as compared to that in the western literature.

Conclusion

Breast carcinomas in our population presents as locally advanced cancer, with predominance of higher histological grade and higher stage in view of lack of or limited access to the early detection services and treatment.