Study of correlation between granulomtous lesion on FNAC and AFB positive TB cases

Dr Rina Kumari; Dr Dhanesh Kumar; Dr R.K. Mishra

Volume : IX, Issue : I, January - 2020

Study of correlation between granulomtous lesion on FNAC and AFB positive TB cases

Dr Rina Kumari, Dr Dhanesh Kumar, Dr R. K. Mishra

Abstract :

Tuberculosis is the commonest infectious disease in the developing world. Many diagnostic tests are devised for its detection including direct smear examination. This study was designed to corelation b/w AFB positive and patients diagnosed to have granulomatous inflammation on Fine Needle Aspiration Cytology using special stains. Materials and Methods. A descriptive cross-sectional survey was done on 100 cases of granulomatous inflammation consistent with tuberculosis diagnosed on fine needle aspiration cytology at the Department of Pathology, JLNMC, Bhagalpur.After reporting granulomatous inflammation on giemsa staining of aspirates from FNAC, unstained slides were subjected to special stains, like ZN. Cases positive for AFB on ZN stain were noted down along with their frequency and percentages. Results. Forty-four cases (62.85%) of AFB positive smears were reported as TB while 26(37.14%) cases were AFB positive were m.tuberculosis negative . Cervical lymph nodes were the most commonly involved site (60%) and males(60%) were affected more (40%) than females. Most cases of AFB-positive smears were associated with epitheloid granuloma wth caseation necrosis (60%)followed by only caseous necrosis(30%)andepitheloid granuloma(10%). Conclusion. Special stains should be done on all granulomatous inflammation cases seen on FNAC for confirmation of TB .