Study of Biochemical Parameters in PCOS induced rat and Treated with Fish oil, Shell fish Oil and Metformin.

Smita B. Pillai; Bhavita Chavan

Volume : VIII, Issue : V, May - 2019

Study of Biochemical Parameters in PCOS induced rat and Treated with Fish oil, Shell fish Oil and Metformin.

Smita B. Pillai, Bhavita Chavan

Abstract :

Polycystic ovary syndrome (PCOS) is a very common endocrine disorder among women in their reproductive age which is characterized by polycystic ovary, hyperandrogenemia and menstrual irregularity. The present study was undertaken to determine the effect of fish oil (Sardine oil) and shell fish oil (Krill oil) in the treatment of PCOS induced female Wistar rats on Protein, Albumin, Globulin, Random Blood Sugar (glucose), Cholesterol, Triglycerides and Blood urea nitrogen. Sixty Wistar albino female rats were divided into five groups each consisting of six rats. The control group received 1%CMC while the other four groups were administered orally with 1% Letrozole, once daily for 21 days. After 21 days the rats were fed with fish oil and Shell fish oil and Metformin for 30 days and 60 days. The results indicated that there was a change in the biochemical parameters after the treatment with fish oil and shell fish oil.