STUDIES ON PHYTOCHEMICAL AND ANTIMICROBIAL ACTIVITY IN Cardiospermum helicacabum L.

Elakkiya; M; Tamilselvi; K

Volume : VII, Issue : II, February - 2018

STUDIES ON PHYTOCHEMICAL AND ANTIMICROBIAL ACTIVITY IN Cardiospermum helicacabum L.

Elakkiya, M, Tamilselvi, K

Abstract :

In the present study was carried out on phytochemical screening and antimicrobial activity of Cardiospermum helicacabum L. leaves and stems extract against some clinical pathogens. Phytochemical compounds were carried out on the different extract the powdered specimens using standard procedures. Soxhlet apparatus were used for the extracting antimicrobial active compounds from the plant leaves and stem powered. In this investigation tannin, flavonoids and terpenoids showed positive results in Cardiospermum helicacabum L. leaves and stem aqueous extract and ethanol extract showed positive results in terpenoids, saponins, steroids, and carbohydrates. Antimicrobial susceptibility test was determined by Bauer et al., 1966 method. Antimicrobial activity against were analyzed against Bacillus subtilis Escherichia coli, Staphylococcus aureus, Klebsiella pneumonia Pseudomonas aeruginosa, Aspergillus niger and Aspergillus flavus. Ethanol and methanol extract was most effective followed by other aqueous extract. Staphylococcus aureus was more sensitive for ethanol and methanol extract of leaves and stem of the tested plants. In this investigation aqueous, acetone and methanol extracts from the leaves and stem of Cardiospermum helicacabum L. exhibit antifungal activity against Aspergillus niger and Aspergillus flavus. The crude extract as well as the isolated compounds found to be active in this study could be useful for the development of new antimicrobial drugs.