Stress hyperglycemia an independent predictor of underlying LV systolic dysfunction

B.Sasi Kumar; G.V.Sentilnathan; P.Arunachalam

Volume : V, Issue : X, October - 2016

Stress hyperglycemia an independent predictor of underlying LV systolic dysfunction

B. Sasi Kumar, G. V. Sentilnathan, P. Arunachalam

Abstract :

Aim: The aim of this study was to assess the incidence of stress hyperglycemia as an independent predictor of underlying Left Ventricular systolic dysfunction in patients with AMI in non diabetic patients and to compare the severity of coronary artery disease in patients with stress hyperglycemia to those with normal glucose tolerance and those known to have DM in the setting of AMI. Design/Methods: A total of 100 patients with AMI (both with ST segment and Non ST segment elevation) were included, of which 73 were male and 27 were female patients. Blood samples were collected at the time of admission and analyzed for blood glucose and cardiac enzyme levels. Echocardiography was performed on 3-5days and left ventricular ejection fraction (LVEF) was measured. Results: In 33.8 % patients with stress hyperglycemia , 54.1 % diabetic patients and 12.2 % patients with normal glucose tolerance had multi vessel disease with significant P value of <.001 Conclusions: We conclude that this study provides further evidence to support the previous finding that stress hyperglycemia is common in AMI in non diabetic patients and also suggests that the severe coronary artery disease is present not only in the diabetes group but also in the stress hyperglycemia group. Statistically association was observed between stress hyperglycemia and underlying severe LV dysfunction in patients with AMI.