Serum Amylase and Serum Lipase Levels in Diabetic Ketoacidosis

Dr. Lakhan Patidar; Dr. S. K. Jain; Dr. K. K. Kawre; Dr. Simmi Dube

Volume : IX, Issue : VI, June - 2020

Serum Amylase and Serum Lipase Levels in Diabetic Ketoacidosis

Dr. Lakhan Patidar, Dr. S. K. Jain, Dr. K. K. Kawre, Dr. Simmi Dube

Abstract :

Background- This study was planned to estimate serum amylase and serum lipase levels in patients presenting with diabetic ketoacidosis (DKA) and to correlate these enzyme levels with clinical presentation and serum triglycerides levels in patients with DKA. Methodology- In this cross sectional study, serum amylase and serum lipase levels of patients presenting with DKA were assessed at admission (day 1) and on day 3. Serum triglycerides levels were assessed at admission (day1). Results- 80 patients with DKA were enrolled. Serum amylase level was raised in 16% at admission (day 1) and in 45% at day 3 with no evidence of acute pancreatitis. A positive correlation of serum amylase and lipase levels with pain in abdomen and serum triglycerides levels at both day 1 and day 3 was observed. Conclusion- In patients with DKA, there is non-specific elevations in serum amylase as well as serum lipase levels irrespective of presenting symptoms (nausea, vomiting and pain in abdomen) with positive correlation with pain in abdomen and serum triglycerides levels.