Seroepidemiological Study of Antistreptolysin O Antibodies in a Tertiary Care Centre in South India

Dr. S. Nikhat Sheerin; Dr. Mohammed Nasaruddin; Dr. Yasmeen Fatima; Dr. V.V. Shailaja

Volume : VII, Issue : XI, November - 2018

Seroepidemiological Study of Antistreptolysin O Antibodies in a Tertiary Care Centre in South India

Dr. S. Nikhat Sheerin, Dr. Mohammed Nasaruddin, Dr. Yasmeen Fatima, Dr. V. V. Shailaja

Abstract :

Introduction: Antistreptolysin O (ASO) antibody titers are commonly employed in the diagnosis of Group A beta-hemolytic streptococcal infections and their sequelae. The present study was undertaken with the aim of estimating the seroprevalence of ASO antibody titres > 200 IU/ml in patients attending a tertiary care hospital in Hyderabad, Telangana. Materials and Methods: A retrospective study of specimens tested during a one and half year period from January 2015 to June 2016 was undertaken. A rapid, latex, slide agglutination method with a lowest detection limit of 200 IU/mL was employed. Demographic details of patients were noted. Results: The prevalence of ASO titres greater than 200 IU/mL was found to be 27 % (71/261) in the study population. Majority of patients were in the age group of 0-20 years with a female preponderance. Conclusions: The seroepidemiological data related to ASO titres from a tertiary healthcare facility in South India was elucidated.