ROLE OF SERUM ALBUMIN AS A PROGNOSTIC FACTOR IN TRAUMATIC BRAIN INJURY

Dr. Puneet Kant; Dr. L N Gupta; Dr. Ajay Choudhary

Volume : VIII, Issue : VIII, August - 2019

ROLE OF SERUM ALBUMIN AS A PROGNOSTIC FACTOR IN TRAUMATIC BRAIN INJURY

Dr. Puneet Kant, Dr. L N Gupta, Dr. Ajay Choudhary

Abstract :

Background Traumatic ain injury still remains a serious concern and one of the leading causes of death and disability, particularly among young adults. Early determination of prognosis after traumatic ain injury is a priority for relatives and physicians involved in the care of these patients. New prognostic information beyond the clinical examination, patient demographics and radiological imaging from admission is needed to allow early prediction of short, mid, and long term outcome of patients with moderate and severe traumatic ain injury. We conducted our study to elucidate the role of serum Albumin as a prognostic marker in traumatic ain injury. 120 patients with moderate to severe head injury (GCS ≤ 13) admitted in the Department of Neurosurgery, PGIMER and Dr. RML Hospital, New Delhi were studied from November 2015 to March 2017. Objectives: To elucidate the role of serum Albumin as a prognostic marker in traumatic ain injury Materials & Methods: 120 patients with moderate to severe head injury (GCS ≤ 13) admitted between November 2015 and March 2017 were studied. Clinical parameters, radiological parameteers, details of surgical/ conservative management, duration of total hospital stay and duration of stay in the ICU were recorded. This was correlated with serum Albumin levels on admission, day 3, day 5 and day 10 following admission. Results: S. Albumin levels on Day 1, 3, 5 and 10 were found to be significantly lower (p<0.001) in Severe TBI as Compared to Moderate TBI. Percentage fall in S. Albumin levels on Day 5 (p<0.011) and Day 10 (p<.0005) were found to be significantly higher in Severe TBI as Compared to Moderate TBI. Mean S. Albumin levels were found to be significantly lower among patients with an unfavourable Glasgow Outcome Score, longer ICU stay and non survival ( p < 0.005). Conclusion: Serum albumin levels can be considered to be a reliable prognostic indicator in patients with traumatic ain injury with no other systemic co morbidities.