Role of Platelet Parameters in Dengue Positive Cases - A Single Centre Experience

Dr. Isha Bansal; Dr S. Jotkar

Volume : VIII, Issue : VII, July - 2019

Role of Platelet Parameters in Dengue Positive Cases - A Single Centre Experience

Dr. Isha Bansal, Dr S. Jotkar

Abstract :

Aim: To study the role of platelet parameters like platelet count (PLT), Mean platelet volume (MPV) and Platelet distribution width (PDW) in dengue positive infection and also to note their relationship with the severity of the disease. Objectives: 1. Take Dengue positive patients 2. Get CBC, CXR, USG of Abdomen. 3. See Relationship of Platelet parameters with severity of disease in the form of pleural effusion , ascites, bleeding manifestation,DHF,DSS. Material and Methodology: The study was done on 78 dengue positive cases during the outeak of dengue infection over a period of 2 months between JULY 2018 to AUGUST 2018. The platelet parameter like Platelet count, Mean platelet volume, Platelet distribution width were noted using BC 3000 plus Mindray Automated Hematology Analyzer ) along with routine blood parameters hemoglobin(Hb), hematocrit, WBC,serum bilirubin, liver enzymes (AST, ALT) and was compared with severity of disease in the form of in the form of pleural effusion , ascites, bleeding manifestation, DHF, DSS. These 100 patients were also grouped into three according to the platelet count (<20,000, 20,000-1,00,000, >1,00,000), and PDW and MPV were compared in these groups. Inclusion Criteria: All patients with clinical features and serologically positive dengue infection above age of >18 years were included. Exclusion Criteria: Other causes of thrombocytopenia like due to infections other than dengue, megaloblastic anaemia, cirrhosis etc. Conclusion:The study focuses the importance of platelet parameters in dengue infection. Significant difference was observed between severity of the thrombocytopenia and severity of the disease (P value -0.013). Platelet count is thus a predictive parameter of DF/DHF/DSS. Low MPV (13fl) shows sensitivity for dengue fever thus reflecting a predictive marker for diagnosing dengue fever in endemic area.