Quantitative cytomorphometry as a tool to assess the cellular alterations of oral mucosal cells following Ortho-pantomography.

Dr. Ritesh Srii

Volume : VIII, Issue : VIII, August - 2019

Quantitative cytomorphometry as a tool to assess the cellular alterations of oral mucosal cells following Ortho-pantomography.

Dr. Ritesh Srii

Abstract :

Background: X-rays forms an integral part of management of diseases that are used commonly in dentistry to arrive at an appropriate diagnosis. During such procedures the rays emitted in the form of ionizing radiations are capable of inducing cytotoxic alterations in exposed oral buccal mucosa cells. Aim: To monitor the cytomorphometric alterations taken place within the exposed buccal mucosal cells before and after orthopantomography. Method: The present study is a cross-sectional study undertaken in the Department of Oral Medicine and Radiology, Dhulikhel hospital, Dhulikhel, Kavre, Nepal. Apparently healthy individuals requiring Orthopantomography, who met the inclusion criteria were involved in this study. Informed consent was taken, after which the pre and post buccal mucosal samples were obtained and stained using Papanicolaou stain. These stained slides were observed using light microscope for recording the cytomorphometric changes. Results: A statistically significant change was observed in the nuclear area (p- 0.03) from the samples obtained from the buccal mucosal smears following exposure to orthopantomography. Conclusion: Buccal mucosal cells exposed to ionizing radiation did show some cytomorphometric alterations following orthopantomography.