PROSPECTIVE RANDOMISED STUDY ON POSTOPERATIVE ANALGESIA FOR CAESAREAN SECTION WITH INTRATHECAL BUPRENORPHINE

Dr.Balasubramanian; Dr.K.Rajachidambaram

Volume : VI, Issue : XII, December - 2017

PROSPECTIVE RANDOMISED STUDY ON POSTOPERATIVE ANALGESIA FOR CAESAREAN SECTION WITH INTRATHECAL BUPRENORPHINE

Dr. Balasubramanian, Dr. K. Rajachidambaram

Abstract :

AIM: To compare the effectiveness of intrathecal 0.5%Heavy bupivacaine and Buprenorphine 60� g w ith 0.5%Heavy bupivacaine for postoperative analgesia in elective caesarean section.

OBJECTIVE: : To evaluate the efficacy , duration of post operative pain relief and to know the quality of analgesia provided by intrathecal opioids added to local anaesthetic agents.

METHODS: The study w as undertaken in 60 patients of ASA I and II posted for elective cesarean section for post operative pain relief.

GroupA – 30 patients – received 1.7ml of hyperbaric 0.5% bupivacaine w ith buprenorphine 0.2ml(60� g).

GroupB – 30 patients – received 1.7ml of hyperbaric 0.5%bupivacaine w ith 0.2ml 0f 0.9% normal saline.

PLACE OF STUDY: CHENNAI MEDICAL COLLEGE HOSPITAL AND RESEARCH CENTER.

RESULTS: - Onset of sensory analgesia is significantly increased(1-31/2min) in patients receiving buprenorphine than control group.

- Onset of motor blockade also significantly increased in study group 1-5min.

- Postoperative analgesia w as upto 13-14hours in groupA(study)w ith

SD.96.33min than control group B 21/2 – 41/2 hours.

- There w as no statistically significant changes in pulse rate, respiratory rate, blood pressure , oxygen saturation and neonatal apgar score.

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- There w as no respiratory depression in study group and few patients had a sedation score >3 w hich is statistically significant. There w as no statistically significant complications in both groups.

CONCLUSION: Anaesthesia w as superior w hen buprenorphine is mixed w ith bupivacaine (0.5%) as compared to bupivacaine alone. So this combination of drugs can be used for postoperative analgesia in elective cesarian section.