Prevalence of metabolic syndrome and its components in patients of hypothyroidism in a North Indian tertiary care hospital.

Mohammad Obaid; Mohammad Ashraf; Sabhiya Majid; Ruheel Ahmad

Volume : VIII, Issue : V, May - 2019

Prevalence of metabolic syndrome and its components in patients of hypothyroidism in a North Indian tertiary care hospital.

Mohammad Obaid, Mohammad Ashraf, Sabhiya Majid, Ruheel Ahmad

Abstract :

Thyroid disorders and metabolic syndrome are both individual risk factors for development of cardiovascular disease. Given the role that thyroid hormones play in regulating energy balance, metabolism of glucose, and lipids, researchers have pointed out towards the possibility of a relationship between hypothyroidism and metabolic syndrome. While the prevalence of metabolic syndrome in hypothyroid patients across the globe has varied from 35 to 50 %, studies in the Indian population have been scanty. In our study we found the prevalence of metabolic syndrome to be 43 % in hypothyroid patients and 26 % in euthyroid patients. Prevalences of raised waist circumference(WC), blood pressure, fasting blood glucose, triglycerides(TG) and lowered HDL in hypothyroid patients were 75%, 28%, 12%, 52% and 65% respectively, out of which WC (0.000), Systolic BP(0.035), TG( 0.002) were significantly elevated. A significant rise in prevalence of metabolic syndrome as well as its individual components is seen in hypothyroid patients. Routine screening for cardiovascular risk factors in patients with thyroid disorders, especially in those with hypothyroidism, may assist in the detection of MetS.