PREVALENCE AND SEVERITY OF THROMBOCYTOPENIA IN DENGUE PATIENTS.

Dr Parvez Bahar Choudhury; Dr Rupjyoti Gogoi

Volume : VII, Issue : I, January - 2018

PREVALENCE AND SEVERITY OF THROMBOCYTOPENIA IN DENGUE PATIENTS.

Dr Parvez Bahar Choudhury, Dr Rupjyoti Gogoi

Abstract :

Introduction: Dengue fever is one of the most prevalent and fastest spreading mosquito-borne arboviral infection occurring in tropical and sub-tropical regions around the world. Despite considerable efforts to control the mosquito populations, dengue fever has emerged, spread and established itself rapidly. The most serious manifestations of the infection are Dengue Hemorrhagic Fever (DHF) and Dengue Shock Syndrome (DSS). Thrombocytopenia is one of the major clinical manifestation and is common in patients with either mild or severe cases of dengue infection. Objectives: Evaluation of prevalence and severity of thrombocytopenia in dengue infection. Material and Methods: The present study was conducted retrospectively for a period of one year. Blood samples were collected from 450 patients experiencing feile illness, clinically consistent with dengue infection. Serological confirmation of dengue infection and evaluation of platelet counts was done in all the serologically positive cases. Results: A total of 450 fever cases were admitted during the study period and among them, 56 (12.4%) were found to be seropositive for dengue. Among the dengue positive cases, 38 were males and 18 were females. Of the seropositive cases,67.8% had thrombocytopenia while the remaining, 32.1% had platelet counts >1 lakh. Out of 38 patients with thrombocytopenia, 25 (65.7%) had mild thrombocytopenia, 08 (21.0%) had moderate thrombocytopenia and remaining 05 (13.1%) had severe thrombocytopenia. Conclusion: This study concludes that thrombocytopenia is highly prevalent in dengue infection. However, the incidence of severe thrombocytopenia and hence bleeding manifestations are less in dengue infection. < clear="all" style="page-eak-before:always;mso-eak-type:section-eak" />