Preoperative Use And Comparison Of Different Opioids Intravenously For The Prevention Of Post-Operative Shivering After Sevoflurane Anaesthesia

Dr Gunadhar Jana; Dr Sudakshina Roy; Dr. Debarshi Jana

Volume : IX, Issue : V, May - 2020

Preoperative Use And Comparison Of Different Opioids Intravenously For The Prevention Of Post-Operative Shivering After Sevoflurane Anaesthesia

Dr Gunadhar Jana, Dr Sudakshina Roy, Dr. Debarshi Jana

Abstract :

A significant number of patients, undergoing Sevoflurane and or Propofol anaesthesia, may develop shivering and hypoxemia, in the immediate post-operative period. However in majority of patients this is relieved spontaneously after some time in fit and healthy patients - no serious problem is posed. As post-anaesthetic shivering increase metabolic rate, oxygen (O2) demand and carbon-di-oxide (CO2) production, it may become hazardous in compromised patient population. Several physical and pharmacological approaches to treatment and prevention of post-anaesthetic shivering have been studied. Pethidine in a low dose has been found to be the most effective and consistent drug in stopping post-anaesthetic shivering. Confusing reports are found in the literature regarding the role of other opioids e.g. Fentanyl in treating post-anaesthetic shivering. Hence, this prospective, randomized, double blind study was conducted in 90 ASA-I patients undergoing operation under general anaesthesia, lasting not more than 1 hour. The patients were divided into 3 groups, – Group-I received Pethidine, Group-II received Buprenorphine and Group-III received Butorphanol. Identical anaesthetic technique was employed for all the patients, namely induction with propofol and maintaining anaesthesia with sevoflurane upto 3vol% using Mapleson-A circuit for spontaneous ventilation. Ambient temperature of operation theatre (OT) and recovery room and temperature of intravenous (IV) fluid were maintained around 30oC. Heart rate, core temperature, oxygen saturation and end-tidal CO2 (ETCO2) were recorded intra-operatively and post-operatively from time to time. Arterial blood gases of shivered patients were done.