Pattern of Dyslipidemia amongst adult Diabetic subjects : Cross Sectional study from tertiary care hospital in Lucknow.

Dr Meeta Pathak; Dr Mandira Sharma

Volume : V, Issue : IV, April - 2016

Pattern of Dyslipidemia amongst adult Diabetic subjects : Cross Sectional study from tertiary care hospital in Lucknow.

Dr Meeta Pathak, Dr Mandira Sharma

Abstract :

<p>&nbsp;Background: Diabetes mellitus (DM) is a common secondary cause of hyperlipidaemia, particularly, if glycaemic control is poor, which in-turn is an important risk factor for atherosclerosis and coronary heart disease. The spectrum of dyslipidemia in diabetes mellitus can include all the various types of dyslipidemia identified in the general population Objectives: To study the prevalence and pattern of dyslipidemia in type 2 diabetes. Material and Methods: It was a cross sectional study, done on type 2 diabetes patients attending medicine outpatient department of Career Institute of Medical Sciences and Hospital, Lucknow between July 2015 to December 2015. All the patients were interviewed with pre-designed Performa. Fasting lipid profile and Glycosylated hemoglobin (HbA1c) of patients were measured. Patients suffering from other causes of secondary dyslipidemia were excluded. Patients having one or more parameters outside the targets recommended by American Diabetes Association (ADA) were considered to have dyslipidemia. Results: Out of 200 diabetic patients enrolled in the study, 120 were male and 80 were female patients. The mean age of study population was 54.8 &plusmn; 10.12 (male: 54.7 &plusmn; 10.65 and female: 54.9 &plusmn; 9.42). Out of 175 DM dyslipidemic patients, 85 patients were having high serum cholesterol level, while lesser no.of patients, 65 had low serum HDL levels. About 125 had high serum triglyceride level, while almost similar number of patients, 105 also had serum LDL levels above normal range. About 100 patients also showed high serum VLDL levels. Conclusion: Majority of type 2 diabetic patients (n=175) were dyslipidimic. The most common pattern of dyslipidemia among males was combined dyslipidemia with high triglycerides (TG) and low High density lipoprotein (HDL) and in females it was high Low density lipoprotein (LDL) and low HDL. The most prevalent lipid abnormality in our study was high TG.Significant relation was found between HbA1c and serum lipid parameters.</p>