OXACILLIN SCREENING FOR METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS

Ms. Sarita Yadav; Dr. Basudha Khanal; Dr. Narayan Raj Bhattarai

Volume : VII, Issue : II, February - 2018

OXACILLIN SCREENING FOR METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS

Ms. Sarita Yadav, Dr. Basudha Khanal, Dr. Narayan Raj Bhattarai

Abstract :

Introduction: Methicillin resistant staphylococcus aureus (MRSA) is a strain of Staphylococcus aureus that is resistant to a large group of antibiotics. Study was aim to screen the isolated S. aureus for Oxacillin resistance by Oxacillin screen agar.

Methods: Clinical specimens obtained from patients in various departments of BPKIHS, and submitted to department of Microbiology for culture and sensitivity were included. Among 90 isolated SA was screened by using cefoxitin disc as per Kirby-Bauer�s disc diffusion method. MRSA were again screened with the Oxacillin screening agar.

Results: Out of these 90; 23(25.56 %) were found to be MRSA and rest 67(74.44%) were Methicillin sensitive staphylococcus aureus (MSSA). Then the Oxacillin screening test showed that 32 isolates were sensitive to oxacillin (35.55%) while 58 were resistant to oxacillin (64.45%).

Conclusion: In this study 26% MRSA was found, which indicated the alarming threats to use the beta lactam antibiotics.