NON-ALCOHOLIC FATTY LIVER DISEASE AND SERUM VITAMIN D

Sohret Yildirim; Suleyman Ahbab; Betul C. Turker; Efnan Calik; H. Esra Ataoglu

Volume : VIII, Issue : II, February - 2019

NON-ALCOHOLIC FATTY LIVER DISEASE AND SERUM VITAMIN D

Sohret Yildirim, Suleyman Ahbab, Betul C. Turker, Efnan Calik, H. Esra Ataoglu

Abstract :

Background: Non-alcoholic fatty liver disease (NAFLD) is associated with metabolic syndrome and insulin resistance. The frequency of NAFLD and vitamin D deficiency are increasing, worlwide. The aim of this study was to evaluate the relationship between vitamin D deficiency and NAFLD. Methods: 148 patients who underwent abdominal ultrasonography (USG) were included in the study. The presence of NAFPD was determined by standard 2-dimensional abdominal ultrasonography. 25 OH vitamin D levels of the patients were measured. Vitamin D levels above 30 ng/ml were sufficient, between 20 and 30 ng/ml were insufficient and below 20 ng/ml were defined as deficiency. All the data provided from the study were recorded and evaluated by using SPSS (Windows 16.0). A p value ≤0.05 or confidence interval of 95% was considered statistically significant. Results: The number of patients with adequate vitamin D levels was 14, the number of those with vitamin D deficiency was 12, and the number of those with severe vitamin D deficiency was 102. Of the 148 patients, 33 had hepatosteatosis according to the abdominal USG. 25 of patients with hepatosteatosis had severe vitamin D deficiency. Conclusion: In our study, serum vitamin D levels were decreased in the majority of patients. Therefore, there was no statistical relation between NAFLD and serum vitamin D levels. Vitamin D deficiency was found to be severe in our hospital population.