Volume : IX, Issue : VII, July - 2020

MUPIROCIN RESISTANCE IN METHICILLIN RESISTANCE STAPHYLOCOCCUS AUREUS

Dr. Deepika Atray, Dr. Anshu Sharma

Abstract :

Irrational use of antibiotics and prolonged hospital stay leading to carriage of MRSA in nose, axilla, perineum are some risk factors for acquiring MRSA infections and its spread in community. Mupirocin is an effective antibiotic used topically for the elimination of MRSA in the carriers. But the long term use of antibiotics has led to emergence of mupitocin resistant strains. Material and methods: 300 S.aureus isolates were processed for antibiotic susceptibility testing and methicillin resistance using cefoxitin disc and mupirocin resistance using 5µg and 200µg disc. Results: In the present study, overall 4% LLM resistance and 3.33% HLM resistance was observed. 5% MRSA and 1.8% MSSA were high level mupirocin resistance while 7.2% MRSA and 2.4% MSSA were low level mupirocin resistance. Conclusion: Low level resistant strains need to be detected, so can be treated with higher concentration of the drug. Judicious use of mupirocin application needs to be done to avoid emerging its resistance.

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Article: Download PDF    DOI : https://www.doi.org/10.36106/gjra  

Cite This Article:

MUPIROCIN RESISTANCE IN METHICILLIN RESISTANCE STAPHYLOCOCCUS AUREUS, Dr. Deepika Atray, Dr. Anshu Sharma GLOBAL JOURNAL FOR RESEARCH ANALYSIS : Volume-9 | Issue-7 | July-2020

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