Mesenteric Microcystic/Reticular Schwannoma: A Diagnostic Dilemma

Dr. Vinod K. Sawaitul; Dr. Shailendra G. Dhawane; Dr. Shashikant V. Dhoble

Volume : V, Issue : III, March - 2016

Mesenteric Microcystic/Reticular Schwannoma: A Diagnostic Dilemma

Dr. Vinod K. Sawaitul, Dr. Shailendra G. Dhawane, Dr. Shashikant V. Dhoble

Abstract :

Background:- Microcystic/ reticular schwannomais a rare variant of schwannoma with a predilection for visceral locations including the gastrointestinal tract. Due to overlapping features with other tumors, unawareness of this tumor type may lead to diagnostic pitfalls. Case:- We here report a case of microcystic/reticular schwannoma arising in the mesentery of a 25-year-old female. The tumor was incidentally discovered by ultrasonography. Observations & Result:- An operation was performed and histological examination revealed a capsulated tumor composed of spindle cells with reticular pattern set within a myxoid stroma. Differential diagnoses were Extra gastrointestinal stromal tumor with myxoid change (EGIST), Microcystic/ reticular schwannoma, low-grade fiomyxoid sarcoma (LGFMS) and aggressive angiomyxoma (AAM). Immunohistochemically, the tumor cells were positive for S-100 protein which was consistent with a peripheral nerve sheath tumor. Conclusion:- Albeit very rare, Microcystic/ reticular schwannoma should be included in the differential diagnosis of mesenteric tumors. The awareness and knowledge about this tumor are needed to achieve the correct diagnosis.