INSULIN RESISTANCE TO COVID-19 INFECTION: PRESENTATION OF AN ORIGINAL CASE

Diana Ofelia Tutasi Guaquipana; Priscilla Elizabeth Machado Unigarro; Jessica Paulina Masapanta Yanchapanta; Ana Ver�nica Cruz Andrade; Luis Gonzalo Chito Ases

Volume : IX, Issue : VII, July - 2020

INSULIN RESISTANCE TO COVID-19 INFECTION: PRESENTATION OF AN ORIGINAL CASE

Diana Ofelia Tutasi Guaquipana, Priscilla Elizabeth Machado Unigarro, Jessica Paulina Masapanta Yanchapanta, Ana Ver Nica Cruz Andrade, Luis Gonzalo Chito Ases

Abstract :

In the city of Wuhan, Hubei province, China, dated December 31, several cases of Atypical Pneumonia of unknown etiology were reported. This was notified to WHO, who subsequently declared it a pandemic due to the increase in cases. The causative agent of the outeak was identified as a new type of virus called SARS-CoV-2, and its disease COVID-19. When people with type 2 diabetes (DM2) develop a viral infection, it may be more difficult to treat due to fluctuations in blood glucose levels and possibly the presence of complications from diabetes. There seem to be two reasons for this. Firstly, the immune system is compromised, making it difficult to fight the virus and likely leading to a longer recovery period. Second, the virus can thrive in an environment of elevated blood glucose.1,2 We present the case of an octogenarian patient, who has a history of DM2, with good control of it. Go to a compatible clinic for COVID-19. After several extension examinations, lymphopenia, double altered coagulation factors, imaging with various peripheral infiltrates in both lung fields, despite treatment and support measures, the patient died due to various complications. Objective: To demonstrate how DM2 works in patients infected with COVID-19, rapidly developing various complications and a poor prognosis. Method: This is a systematic review of insulin resistance and COVID-19 infection, emphasizing its clinical characteristics and short-term complications. Conclusion: COVID-19 infection is not primarily a metabolic disease, but proper glucose control and lipid levels are key in these patients. This approach is important in addressing the well-established metabolic complications of this comorbidity. Furthermore, effective monitoring of these metabolic parameters would help us prevent and improve the acute effects of this virus, by reducing the local inflammatory response and blocking its entry into cells.