Impact of BMI on clinical, endocrine and metabolic profile of Indian PCOS Women

Dr. Vinita Sarbhai; Dr Mohini Paul

Volume : V, Issue : IV, April - 2016

Impact of BMI on clinical, endocrine and metabolic profile of Indian PCOS Women

Dr. Vinita Sarbhai, Dr Mohini Paul

Abstract :

<p>&nbsp;Objective: To assess the differences between non obese and obese subgroups of women with PCOS with regard to clinical, endocrine and metabolic profile of Indian PCOS women according to ESHRE/ ASRM criteria. Method: Fifty healthy women who were diagnosed to have PCOS according to ESHRE/ ASRM criteria were evaluated. Patients with BMI&lt;23 kg/ m2 were put in Lean PCOS Group and patients with BMI&gt;23 kg/m2 were labelled as overweight / obese PCOS. Patients were examined and investigated after a detailed history with special reference to menstrual cycles, features of hyper-androgenism, dyslipidaemia, metabolic syndrome, insulin resistance, hormonal profile and ultrasound morphology. Results and conclusions: The present study reveals that obesity, seen in 56% of our patients, plays an important role in clinical, hormonal and metabolic alterations in women with PCOS. Although clinical features, glucose intolerance, and gonadotrophin alterations did not vary significantly with BMI, ovarian morphology, hyperandrogenism, and metabolic disturbances like insulin resistance were accentuated with obesity.</p>