Identification and comparison between alcoholic and non-alcoholic groups of Alcohol Abuse Using Laboratory Test GGT, AST, ALT And MCV through CAGE and AUDIT questionnaires

Alif Muzzafar Sofi; Arsalaan F Rashid; Vina Vaswani; Farida Noor; Sajad

Volume : IX, Issue : V, May - 2020

Identification and comparison between alcoholic and non-alcoholic groups of Alcohol Abuse Using Laboratory Test GGT, AST, ALT And MCV through CAGE and AUDIT questionnaires

Alif Muzzafar Sofi, Arsalaan F Rashid, Vina Vaswani, Farida Noor, Sajad

Abstract :

The alcoholics are identified by CAGE and AUDIT questionnaires. CAGE and AUDIT had a significant relationship with laboratory investigations in establishing case of chronic alcohol abuse. Laboratory investigations (LFT) differentiate the liver enzyme level in chronic alcohol abusers from non alcoholics. It is seen that compared to non-alcoholics, in alcoholics biomarkers (GGT, AST, ALT and MCV) were increased significantly. Increased Biomarkers were associated with alcoholism and alcoholic dependence. In alcoholics it is seen that all biomarkers had positive correlation with AUDIT questionnaire as compared to CAGE questionnaire. There is a strong positive correlation of AUDIT questionnaire with CAGE questionnaire. CAGE has more screening value between alcoholics and non-alcoholics while in comparison to the AUDIT which has more scoring value regarding alcohol consumption. While supplementing CAGE and AUDIT with laboratory investigation can be a predictor of alcoholism. Another important conclusion was the liver enzyme (GGT, AST, ALT) and MCV level can be differentiated between chronic alcohol abusers and non alcoholics. So this study supports that chronic alcohol abuse can be detected using CAGE and AUDIT questionnaires and laboratory investigations.