HIV neuropathy drug naive PLHA patients and it's correlation with glycemic status in central India.

Somnath Singh Raghuvanshi; Tribhuvan Nath Dubey; Himanshu Sharma; Rita Saxena

Volume : IX, Issue : I, January - 2020

HIV neuropathy drug naive PLHA patients and it's correlation with glycemic status in central India.

Somnath Singh Raghuvanshi, Tribhuvan Nath Dubey, Himanshu Sharma, Rita Saxena

Abstract :

The sensory neuropathies are still prevalent as the most frequent neurological disorder associated with HIV infection and its treatment with ART. There are two major types of HIV-associated distal sensory peripheral neuropathies: primary HIV-associated distal sensory polyneuropathy (HIV-DSP) and ART toxic neuropathy (ATN), together which affect approximately 30–67% of patients with advanced HIV disease.AIM: Aims : association of HIV neuropathy & its correlation with glycemic status. Material & methods After obtaining prior ethical clearance, treatment na�ve PLHA (person living with HIV/acquired immunodeficiency syndrome (AIDS)) patients were included in the study and we carried out a cross‑sectional study of the HIV seropositive patients in inpatient and outpatient clinic of the Gandhi Medical College, Bhopal, from December 2011 to December 2012.Results: Impaired fasting glucose was significantly higher in neuropathy group by NCS examination (61.9%) than non-neuropathy group (31.2%), p=0.009 . Impaired glucose tolerance is significantly higher in clinical neuropathy group (75.9%) than non-neuropathy group (28.3%), p=0.009. Conclusion : The dysglycemia is more common in the hiv patients and both dysglycemia and hiv associated with neuropathy or hiv patients are more prone to dysglycemia.