HISTOPATHOLOGICAL STUDY OF VESICULOBULLOUS LESIONS OF THE SKIN: A STUDY AT TERTIARY CARE HOSPITAL

Neha Agrawal; Dilip Sarate; Pradeep Umap

Volume : VIII, Issue : II, February - 2019

HISTOPATHOLOGICAL STUDY OF VESICULOBULLOUS LESIONS OF THE SKIN: A STUDY AT TERTIARY CARE HOSPITAL

Neha Agrawal, Dilip Sarate, Pradeep Umap

Abstract :

Background: Vesiculobullous lesions are not uncommon in dermatological practice and present with blister formation which in some instances, are fatal if untreated. They may occur in many dermatosis which include various inflammatory, infective, autoimmune, drug induced as well as genetic conditions. Histopathology study of skin biopsies is one of the useful techniques in the investigation of vesicullobullous lesions. Aims and Objective: To study histopathological features of vesiculobullous lesions and to determine the distribution in age, sex group and the most common subtype in this region. Materials and Methods: A total number of 44 cases of clinically diagnosed blistering disorder were included. In the present study male patients were 25 (56%) & female patients were 19 (43%) . Male : female ratio was 1.3:1.The two year retrospective study was carried out in the Department of Pathology in Government Medical college Akola in collaboration with the Department of Skin and V.D. The duration of study was from January 2017 to December 2018. Result: In the present study amongst 44 cases, Pemphigus vulgaris was diagnosed in 62% cases and was detected the most common type, followed by Bullous pemphigoid (18%) and Pemphigus foliaceus (11%), Dermatitis herpetiformis (7%) & erythema multiforme (2%). Conclusion: This emphasizes the importance of skin biopsy in analysing the morphological features along with clinical features in the diagnosis of vesiculobullous disorders of skin.