HISTOPATHOLOGICAL SPECTRUM OF GASTROINTESTINAL LESIONS -5 YEARS STUDY IN TERTIARY CARE HOSPITAL

Bhagat Shweta; Singh Kuldeep

Volume : VII, Issue : XI, November - 2018

HISTOPATHOLOGICAL SPECTRUM OF GASTROINTESTINAL LESIONS -5 YEARS STUDY IN TERTIARY CARE HOSPITAL

Bhagat Shweta, Singh Kuldeep

Abstract :

A total of 12937 surgical specimens were received during the study period. Twenty one hundred (2100) cases of GIT tumors were diagnosed histologically. One thousand nine hundred eighty two (1982) GIT lesions were diagnosed as non- neoplastic, while one hundred eighteen (118) were diagnosed as neoplastic. Fifty- theee (53) tumors were diagnosed as benign neoplastic lesions, while sixty five (65) tumors were diagnosed as malignant neoplastic. Prevalence rate of 2100 GIT lesions was 16.23% surgical specimens. Prevalence rate of non- neoplastic lesions was 15.32%, neoplastic GIT lesions was 0.91% with benign GIT lesions 0.41% and malignant GIT lesions 0.50%. Youngest patient was a 4-year-old boy, while oldest patient was 90 years old male. Highest number of GIT tumors were seen in the age group 10- 19 years and 20- 29 years. Male to female ratio was 2.65:1. Majority of non- neoplastic and neoplastic lesions were observed in male subjects. Appendix was the most common site for non-neoplastic lesions. Large intestine was the most common site for benign and oesophagus for malignant tumors of GIT, followed by stomach and large intestine.48 cases of meckels diverticulum were observed.Majority of the malignant tumours of the oesophagus were squamous cell carcinoma, followed by adenocarcinoma and adenosquamous carcinoma.Chronic superficial gastritis was the most common non- neoplastic lesion of stomach. Hyperplastic or inflammatory polyp were the most common polyps of the stomach. Adenocarcinoma was the most common malignant gastric tumour, followed by GIST. Non-specific inflammatory lesion was the most common non-neoplastic lesion of small intestine followed by ischemic congestive pathology followed by granulomatous pathology.Tubular adenoma and hyperpastic polyps were the most common polyps of the small intestine. NO malignant small intestine lesion was observed.Acute appendicitis was the most common non-neoplastic lesion of appendix. 2 cases of mucinouscystadenoma were the benign tumours observed in appendix. Carcinoid was the most common malignant lesion of the appendix, followed by mucinous cystadenocarcinoma. Non-specific inflammation was the most common non-neoplastic lesion followed by colitis followed by hirschsprung disease in large intestine. Juvenile/retention polyp were the most common polyps of the large intestine, followed by hyperplastic polyp, tubular adenoma, tubullovillous adenoma.Majority of the malignant large intestinal tumours were adenocarcinoma, followed by non-Hodgkin‘s lymphoma and GIST. Haemorrhoids followed by fistula-in- ano were the most common non –neoplastic lesions of the anal canal. Squamous cell carcinoma was the most common malignant anal canal tumour.