Volume : VI, Issue : VII, July - 2017

High maternal viral load key to vertical transmission of hepatitis B

Dr Shweta Mishra, Dr Manju Varma

Abstract :

 Objectives: To  assess the risk of perinatal hepatitis B virus (HBV) transmission by quantitative HBV DNA.

 

Method: The present study was carried out at MLN Medical College Allahabad a total of 5000 pregnant patients were screened for HBV infection. HBsAg positive women were enrolled for the study. Infectivity status was determined by HBeAg positivity by Elisa and quantitative HBV DNA by RT PCR. At the time of delivery cord blood was taken to assess the perinatal transmission.

 

Result: . Total vertical transmission was 37.5% .In all HBeAg positive mother 63.63% showed vertical transmission. In HBsAg positive women with High viral Load (>1x10⁵ copies/ml)showed 90% vertical transmission. Thus vertical transmission depends upon the HBV viremia levels.

Keywords :

Article: Download PDF    DOI : https://www.doi.org/10.36106/gjra  

Cite This Article:

Dr Shweta Mishra, Dr Manju Varma, High maternal viral load key to vertical transmission of hepatitis B, GLOBAL JOURNAL FOR RESEARCH ANALYSIS : VOLUME-6 | ISSUE‾7 | JULY -2017

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