HER-2 POSITIVE BREAST CANCER, GENERAL DESCRIPTION:

Leonardo David Villacres; Maria Jose Munoz; Veronica Perlaza; Elizabeth Romero; Marco Leon Montenegro; Carolina Saldana; Alexander Jara; Rene Munoz

Volume : VIII, Issue : II, February - 2019

HER-2 POSITIVE BREAST CANCER, GENERAL DESCRIPTION: "HOSPITAL ONCOLOGICO GRAL. SOLON ESPINOSA AYALA" SOLCA QUITO-ECUADOR

Leonardo David Villacres, Maria Jose Munoz, Veronica Perlaza, Elizabeth Romero, Marco Leon Montenegro, Carolina Saldana, Alexander Jara, Rene Munoz

Abstract :

Objectives: to describe the demographic variables, racial groups and to evaluate the survival in women older and younger than 60 years old diagnosed with HER-2 east cancer positive. Methods: A retrospective analysis was carried out during the years 2010 and 2015 with the diagnosis of HER-2 east cancer positive, the crossing of variables was performed with Chi square or Fisher‘s exact test when necessary, the estimation of Survival was performed using the Kaplan Meier method. Results: The present data reported an overexpression of HER2 in 11.58%, occurring more frequently in women under 60 years old in 82.9%, with the most frequent stages II and III, indigenous people as Afro-Ecuadorians represent HER-2 positive in 22.2% being more frequent in the group of Latin Americans non-indigenous or afro-ecuadorians, with respect to survival, women with positive HER-2 east cancer under 60 years old have an average survival of 62.3 months and those over 60 years old 66.2 months; 95% IC (58.7 - 67.33 months). Conclusion: these are the first analyzes in Ecuador descriptively regarding HER2 east cancer, it is necessary to know the response rate in different scenarios such as neoadjuvant, adjuvant, metastatic, as well as identify the reality of east cancer in groups of vulnerable women as are indigenous and afro-descendant people.