Gastric perforation as a result of Candida Albicans infection- a rare entity

KUNAL CHOWDHARY; MUZZAFAR ZAMAN; ALIYA SHAH; KAPIL SINDHU; GULNAR; RAHUL YADAV; PIYUSH KUMAR SINHA; RAJAT PAL; NARENDER BHATI; RAHILLA  TABASSUM

Volume : VIII, Issue : I, January - 2019

Gastric perforation as a result of Candida Albicans infection- a rare entity

Kunal Chowdhary, Muzzafar Zaman, Aliya Shah, Kapil Sindhu, Gulnar, Rahul Yadav, Piyush Kumar Sinha, Rajat Pal, Narender Bhati, Rahilla Tabassum

Abstract :

Introduction: Fungal microorganisms are unusually rare cause of gastric and duodenal perforation. Most of the cases of gastroduodenal perforation occur as complication of peptic ulcer diseases (PUD), regular use of non-steroidal anti-inflammatory drugs (NSAID) and gastric cancer. Cases: Here we are reporting two cases of 40 and 50 years old male patients who presented with similar history of sudden onset pain in epigastric region for 10-12 days with history of intake of NSAID for more than 2 year . An emergency exploratory laparotomy was done for peritonitis and gastric perforation was repaired by modified Graham�s repair. The wedge biopsy was taken from the gastric perforation site which revealed Candida growth. Postoperative period was uneventful. Patients treated with antifungal drug Fluconazole and discharged from hospital. In follow up of 2 months , patient doing well. Conclusion: When upper gastrointestinal perforation is seen in an middle aged or elderly patient, it is necessary to consider not only malignant disease or ulcer but also opportunistic infection such as Candida infection to reduce the signi cant morbidity and mortality.