EXPERIMENTAL STUDY ON THE ROPANA EFFECT OF CHANDANADI TAILA IN SHUDDHA VRANA

Dr. Sukrant Sharma; Dr Malini Thejas; Dr. Ashanka Bhardwaj; Dr. Sarabjeet Kour

Volume : IX, Issue : III, March - 2020

EXPERIMENTAL STUDY ON THE ROPANA EFFECT OF CHANDANADI TAILA IN SHUDDHA VRANA

Dr. Sukrant Sharma, Dr Malini Thejas, Dr. Ashanka Bhardwaj, Dr. Sarabjeet Kour

Abstract :

Vrana and its management are the fundamental practice of shalya tantra. Ropana means the factors which actively promote or quicken the healing process. Acharya Susruta in his treatise Susruta Samhita mentions about 60 upakramas for the treatment of vrana. One among them is ropana taila. This is an experimental study on Wistar albino rats to find out the ropana effect of Chandanadi taila in Shuddha vrana (tidy wounds) with excision wound model. There were 3 groups- control, standard and test, each group containing 6 rats. In control group no intervention was there. In standard group Povidone iodine ointment and in test group Chandanaadi taila was given as external application. Study period was 24 days. Observational parameters were wound contraction, period of epithelialisation, histopathology and hydroxy proline estimation, assessed on 24th day. Epithelialisation and Hydroxyproline parameters were statistically higher in trial group compared to standard. Histopathology showed higher density of collagen and normal cytoarchitecture compared to control and standard groups. Wound contraction rate was similar in standard and test groups. A pilot clinical observational study on 6 patients of shuddha vrana showed significant improvement in wound contraction, epithelialisation and reduction in pain and tenderness.