EVALUATION OF ANTIOXIDANT PROPERTIES OF A PIGMENT MOLECULE ISOLATED FROM RADIORESISTANT BACTERIAL STRAIN INM-2

Neha Chausali; Raj Kumar

Volume : IV, Issue : IX, September - 2015

EVALUATION OF ANTIOXIDANT PROPERTIES OF A PIGMENT MOLECULE ISOLATED FROM RADIORESISTANT BACTERIAL STRAIN INM-2

Neha Chausali, Raj Kumar

Abstract :

Moleculesoffers radioresistantto an organism can be exploited as radioprotective drug for the human uses. Bacterial pigment assumed to be one of these molecules as itpossesses antioxidant properties.Present investigation was carried out to isolate a radioresistant bacteria (INM-2) and evaluation of its antioxidant properties. We have found that isolated bacterium wasradioresistant as it survived under high doses of gamma radiation i.e. 7.5 -10 kGy. Antioxidant properties of pigmentextracted from INM-2 were analysed through reducing power assay, DPPH and lipid peroxidation assay.Results of the study showed that isolated pigment could inhibit free radicals 30 to 35%. It can be assumed from the results that pigment isolated from bacterium (INM-2) having good free radical scavenging properties and may be one of the molecules which contribute to its radioresistant property