Evaluation of abnormalities in liver function test and etiology of Hepatitis B Virus at a tertiary care center Jaipur Rajasthan.

Malla Rupesh Kumar; Shanikant Singh; Rachna; Bhawani Shankar Verma; Abhishek Sharma

Volume : VIII, Issue : XII, December - 2019

Evaluation of abnormalities in liver function test and etiology of Hepatitis B Virus at a tertiary care center Jaipur Rajasthan.

Malla Rupesh Kumar, Shanikant Singh, Rachna, Bhawani Shankar Verma, Abhishek Sharma

Abstract :

Background HBV infection can lead to variable clinical outcomes, ranging from self-limiting acute hepatitis to active chronic hepatitis, cirrhosis and hepatocellular carcinoma. Aims: - To study the evaluation of abnormalities liver function test and etiologies of hepatitis B Virus at a tertiary care center Jaipur Rajasthan. Material and Methods: A total of 147 patients with the clinical diagnosed with HBV positive patients with a liver function test. This is a record-based study from April 2019 to November 2019. Data on clinical characteristics, laboratory parameters, immediate outcome, and analysis was performed in the department of biochemistry and microbiology. Results: A total of 147 patients were positive by the hepatitis B virus. Out of these, Total males were 66.0% and female 34.0%. The mean age of patients with hepatitis B was 31-45 years is most predominant, in the female is 38% and 30% in males. Clinical Risk value of liver function test were serum Bilirubin >5 mg/dl (15.6%), SGOT & SGPT is >500 IU/L (17.6%) and ALP is (49.7%). Clinical features were similar without any complications or mortality. Significant elevations in hepatic enzymes were seen in mixed infection due to HBV. Conclusion: While LFTs abnormalities in HBV are common, HBV infection was associated with increased risk in liver diseases. So LFTs are a helpful screening tool to identify risk factors of the liver in patients of the hepatitis B virus