Evaluating Musculoskeletal Complications Among Individuals With Diabetes Mellitus

Dr. Simran Maheshwari; Dr. Subhan Quraishi; Dr. Babita Ghodke

Volume : III, Issue : VI, June - 2014

Evaluating Musculoskeletal Complications Among Individuals With Diabetes Mellitus

Dr. Simran Maheshwari, Dr. Subhan Quraishi, Dr. Babita Ghodke

Abstract :

Indian traditional health care system (Ayurveda) named Rasayana proposed Phyllanthus emblica Linn. (syn. Emblica officinalis), commonly known as Indian gooseberry or amla, family Euphorbiaceae, is an important herbal drug used in unani (Graceo - arab) and ayurvedic systems of medicine. The plant is used both as a medicine and as a functional food to promote vitality and vigor. E. Officinalis is highly nutritious and could be an important dietary source of vitamin C, amino acids, and minerals. Although, the E. Officinalis extract exhibits higher levels of antioxidant activity, the bioavailability of phenolic acids in the processed fruit is still poorly known. Therefore, in the present study, gallic acid efficacy as an antioxidant was evaluated in two different samples of E. Officinalis. Reliable and feasible HPLC and UFLP methods with diode array detection have been developed and compared for the determination of gallic acid in E. Officinalis dried fruit sample (DFS) and dried processed fruit sample (DPFS) prepared according to one of the Ayurveda principles. The antioxidant effects of both the extracts have also been compared with standard gallic acid by different antioxidant tests like DPPH and ABTS. The amount of gallic acid (20.16 mg/100g) in DPFS was higher in contrast to DFS (8.02 mg/100g) of E. Officinalis fruit which demonstrated higher antioxidant activity. Additionally, It has also been found that gallic acid accounts for approximately 35-71% of the antioxidant activity. UFLP system showed rapid and effiecint determination of gallic acid samples in comparison to HPLC system.