Etiology and Outcome of acute febrile encephalopathy amongst adults admitted at a tertiary care center

Dr. Shivangi Sharma; Dr. V.K.Nandmer; Dr. R.S.Jagat

Volume : IX, Issue : VIII, August - 2020

Etiology and Outcome of acute febrile encephalopathy amongst adults admitted at a tertiary care center

Dr. Shivangi Sharma, Dr. V. K. Nandmer, Dr. R. S. Jagat

Abstract :

Background- The present study was conducted at a tertiary care centre to analyze the cause as well as outcome of encephalopathy following short feile illness in adults (> 14 years old). Methodology- The present study was conducted as a prospective observational study on patients presenting with fever and altered mental status at Department of General Medicine, Gandhi Medical College and associated Hamidia Hospital, Bhopal for a period of 18 months i.e. from 1st December 2017 to 31st May 2019. All the patients were subjected to detailed evaluation with clinical history and systemic examination and investigations. CSF analysis and neuroimaging was also conducted. Results- A total of 507 patients were included and majority of patients had tubercular meningitis followed by bacterial meningitis. The present study documented significantly higher mortality in patients with tubercular meningitis who presented with abnormal finding in neurological imaging (p<0.05). Conclusions Conclusion-, CNS infections are causes of acute feile encephalopathy, and the most common infection was tubercular meninigitis and bacterial meningitis. Mortality was significantly higher in tubercular meningitis and neurological imaging with abnormal finding also had significant impact on mortality.