Effects of anti-solvent flow rate in the microfluidic preparation of nanoparticle for biomedicine application

Mahdi Aghajani

Volume : VIII, Issue : I, January - 2019

Effects of anti-solvent flow rate in the microfluidic preparation of nanoparticle for biomedicine application

Mahdi Aghajani

Abstract :

Microfluidic technology, as a new and efficient method, can be used to provide nanomaterials in biomedical applications and to evaluate the crystallization process for the generation of nanoparticles. In crystallization approach using anti-solvent flow, can precisely control the physical properties of the nanoparticles obtained, including particle size, polydispersity index (PDI), stability and encapsulation efficiency. This operating and convenient method has led to an increase in the researchers‘ attention to nanoparticle manufacturing in this method for pharmaceutical and medical applications. In the current short communication, effects of anti-solvent flow rate as an important parameter in crystallization using microfluidic devices is presented on the particle size, PDI and stability of nanoparticle intended for biomedical applications.