Effect of Obesity on Lipid profile, Liver Enzymes and Cardiac Enzymes among Students (Male) of Aljouf University

Mohammad Najmuddin Khan

Volume : VII, Issue : I, January - 2018

Effect of Obesity on Lipid profile, Liver Enzymes and Cardiac Enzymes among Students (Male) of Aljouf University

Mohammad Najmuddin Khan

Abstract :

Introduction: The prevalence of obesity has risen dramatically in past several decades. Hormonal and genetic factor are rarely the cause of childhood obesity. Because obese adult may suffer life long physical and emotional consequences, this imperative to discuss prevention with parents during well- child examinations. Purpose of the study was to see the effect of Obesity on Lipid profile, Liver Enzymes and Cardiac Enzymes among Students (Male) of Aljouf University. About fifty male students were selected from Aljouf University.

Materials & Methods: Their age ranged from19 to 29 years. They were divided into three groups. First group (N=20) having BMI more than 30 was considered as obese group, second group (N=20) was considered as overweight having BMI more than 25 but less than 30 and third group (N=10) was considered as normal weight group having BMI less than 25. Fasting blood samples were analyzed for Blood Cholesterol, Triglycerides, low density lipoprotein cholesterol (LDL-C) and high density lipoprotein cholesterol (HDL-C), liver enzymes and cardiac enzymes.

Results & Discussion: Independent �t� test was applied to compare mean difference. In obese group, significant higher cholesterol and triglycerides were observed. On the contrary, obese group had significant lower HDL-C concentration than the non-obese group. The adult obese has relatively larger changes in serum lipids at any given level of obesity. On the average, the more fat, the more likely an individual will be dyslipidemic and to express elements of the metabolic syndrome. Increased triglycerides level in obese impaired lipolysis which reduced the HDL-C concentrations. The obtained results for ALT and ALP are comparatively lower for obese and over weight than normal group but lie within normal range and GGT is higher in obese and over weight than normal group within normal range. Obtained results in present study are found to be within acceptable range.

Conclusion: Obesity is assumed to cause hyperlipidaemia and hypercholesterolaemia , considered a risk factor for atherosclerosis. In fact, increase in the incidence of coronary heart disease, congestive heart failure and strokes are associated with obesity.