Effect of laparoscopic cholecystectomy on liver function: A single institution study at a District level hospital.

Zahoor Ahmed Naikoo; Hakeem Vaqar; Akhter Ganie; Malik Munfat

Volume : VII, Issue : II, February - 2018

Effect of laparoscopic cholecystectomy on liver function: A single institution study at a District level hospital.

Zahoor Ahmed Naikoo, Hakeem Vaqar, Akhter Ganie, Malik Munfat

Abstract :

Background:The introduction of minimal access surgery for gallbladder surgery has revolutionized the treatment of gallstones. The present study has been undertaken to see the changes in liver function tests (LFTs) after laparoscopic/open cholecystectomy and to know the clinical significances of such disturbances

Aims and objectives: To compare and correlate change in LFT in patients who underwent LC to those who underwent OC.

Material and Methods : The present study was conducted in Jawaharlal Lal Nehru Memorial hospital Srinagar in the department of surgery. A total 1800 patients of cholelithiasis were included in this study from Dec 2014 to Dec 2017. Three blood samples were taken, pre-operatively; 24 hours after surgery;72 hours after surgery for comparison of the enzyme level alterations.

Results: In LC patients, there were rise in the levels of serum bilirubin, AST and ALT after 24 hrs of surgery from the preoperative value and then again fall was noted after 72 hrs of surgery.

Conclusions: An elevation of serum liver enzymes after laparoscopic cholecystectomy occurs due to transient decrease in splanchnic blood flow. These changes return to normal in 3-4 days after procedure and they have no clinical consequences in patients with normal hepatic function