EFFECT OF INTRAVENOUS MAGNESIUM SULPHATE ON PATIENTS UNDERGOING CRANIOTOMY FOR MENINGIOMA EXCISION

Premkumar D; Yashwant Dhawale; Aditya Agarwal

Volume : IX, Issue : VI, June - 2020

EFFECT OF INTRAVENOUS MAGNESIUM SULPHATE ON PATIENTS UNDERGOING CRANIOTOMY FOR MENINGIOMA EXCISION

Premkumar D, Yashwant Dhawale, Aditya Agarwal

Abstract :

A total of sixty patients scheduled for meningioma excision were divided into two groups of 30 each. Group M patients received 30 mg/kg of magnesium sulphate diluted up to 20 ml with 0.9% NS over 15 mins during preinduction time, followed by infusion of 10 mg/kg/hr. Intraoperatively till dura closure. Group C patients received 20 ml of 0.9% NS preinduction, followed by infusion intraoperatively till dura closure. The vitals were Recorded Pre-induction,Post-induction,Post-intubation, Intra-operatively and at 3rd,6th, 12th and 24th postoperative hour. Post-operative magnesium levels were assessed immediate post op , 6th hour and 12th hour. The data obtained were statistically analysed using IBM SPSS software. The demographic characters, baseline vitals & duration of surgery were comparable. Intraoperative HR, MAP, Inhalational agent ,opioid & Neuromuscular blocker requirement were significantly lesser in group M(p<0.005).