Diagnostic challenges in cartilaginous bone tumours - Incisional / Excisional Biopsy

Dr. Ravi Narayan.H; Dr. Vinay Kumar.G; Dr. Hana A.K; Dr Karpagam Janardhan

Volume : IX, Issue : VII, July - 2020

Diagnostic challenges in cartilaginous bone tumours - Incisional / Excisional Biopsy

Dr. Ravi Narayan. H, Dr. Vinay Kumar. G, Dr. Hana A. K, Dr Karpagam Janardhan

Abstract :

Cartilaginous tumours are among the most common tumours of the appendiceal skeleton, which share a common characteristic feature of production of chondroid matrix by the tumour cells and range from benign to intermediate to malignant behaviour. Distinguishing cartilaginous lesions, especially benign versus malignant lesion is a diagnostic challenge for the pathologists and require correlation with clinical, radiological (including CT, MRI), special stains and IHC for a definite diagnosis as there is no gold standard to resolve this challenge. This challenge jumps multifold, when small incisional biopsy material is evaluated, which may not represent the entire lesion. Accurate diagnosis a critical step which can affect the treatment protocols, which may range from simple curettage and bone grafting to amputation, irradiation or palliative management. Here we present 4 rare cartilaginous tumours, where HPE of incisional biopsy and excisional biopsy yielded different diagnosis. One of the case is suggestive of metachondromatosis, which is a very rare lesion.