Diagnostic and prognostic evaluation of Multiple Myeloma

Guari Shanker Lal; Subhash Chandra Jha; Bibhuti Bhusan Prasad

Volume : VIII, Issue : VI, June - 2019

Diagnostic and prognostic evaluation of Multiple Myeloma

Guari Shanker Lal, Subhash Chandra Jha, Bibhuti Bhusan Prasad

Abstract :

BACKGROUND: Multiple myeloma (MM) is an incurable clonal B-cell malignancy due to malignant proliferation of plasma cells, with an annual incidence of 1% of all malignancies. . AIM: To study the diagnostic epidemiological features and prognostic features . MATERIALS AND METHODS: We conducted a retrospective study at our institute to identify patients diagnosed as MM from 2017 to 2018. We studied diagnostic, ptognostic and clinical profile. RESULTS: Median age at diagnosis is 63 years (range: 45–90 years). IgG myeloma was the most common type seen in 62% of patients. In our study anemia was most common presentation. All cases had plasma cells more than 10% in bone marrow CONCLUSION: Multiple myeloma is common malignancy of Bihar, India in older population. Older patients presenting with refractory anemia must be evaluatyed for plasma cell dyscrasias , especially protein lectrophoresis and bone marrow study could clinch diagnosis in almost 100% cases.