Volume : V, Issue : IX, September - 2016
Detection and Genomic Characterization of Carbapenemase producing Pseudomonas aeruginosaisolates in Chronic SuppurativeOtitis Media(CSOM)
Dr. D. Neelaveni, Dr. P. Sankar
Abstract :
Introduction: Chronic Suppurative Otitis Media is a common infection in the middle ear and an important cause ofheå impairment in developing countries. Aims and Objectives: To determine the Carbapenemase producing Multi drug resistant (MDR) Pseudomonas aeruginosa isolates in CSOM. Materials and Methods: 140 ear swabs were collected from 130 patients with CSOM. The isolates were identified and tested for antimicrobial susceptibility.Pseudomonas isolates with MIC >32 were selected for Carbapenemase production. Results: The Predominant isolate was Pseudomonas aeruginosa36%.Among 24 MDR Pseudomonas isolates 29.1% and 37.5%were confirmed as MBL producer by phenotypic Modified Hodge test &combined disk test respectively and 13 were positive for OXA genes&all were negative for IMP & VIM genes by molecular method. Conclusion: The study concludes that Ceftazidime resistance should be considered as an indicator for detection of resistant enzymes pattern in antimicrobial susceptibility tests
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DOI : https://www.doi.org/10.36106/gjra
Cite This Article:
Dr.D.Neelaveni, Dr.P.Sankar Detection and Genomic Characterization of Carbapenemase producing Pseudomonas aeruginosaisolates in Chronic SuppurativeOtitis Media(CSOM) Global Journal For Research Analysis,Volume : 5 | Issue : 9 | September 2016
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Dr.D.Neelaveni, Dr.P.Sankar Detection and Genomic Characterization of Carbapenemase producing Pseudomonas aeruginosaisolates in Chronic SuppurativeOtitis Media(CSOM) Global Journal For Research Analysis,Volume : 5 | Issue : 9 | September 2016