Volume : IX, Issue : VI, June - 2020

Correlation of Hyponatremia with severity of Hepatic Encephalopathy

Dr. Umakant Boke, Dr. Rahul G Vaidya

Abstract :

Aim: To assess the frequency of hyponatremia in patients with hepatic encephalopathy (HE) and to correlate the severity of hyonatremia with grade/severity of HE at presentation. Study Design: Observational study. Place and Duration of Study: Hangal Shri Kumareshwar Hospital, Bagalkot, Karnataka, from January 2019 to January 2020. Methodology: A total of 62 patients with hepatic encephalopathy were studied. The HE was graded according to the West Haven classification (4 grades) and level of serum sodium was noted in each patient at presentation. Severity of Hepatic Encephalopathy and hyponatremia was correlated using the Freeman – Halton extension of Fisher’s exact probability test. Results: Out of 62 patients, 36 (58.06%) had serum sodium less than 135 meq/L. Of all the patients with HE, 37 had grade I HE, 16 had grade II HE, 9 had grade III HE and none had grade IV HE. Only 2 (7.7%) patients with normal serum sodium had grade III-IV HE, as compared to 7 (19.4%) patients with hyponatremia (p=0.03). Conclusion: Hyponatremia was a common feature in patients with hepatic encephalopathy and the severity of hyponatremia correlated with the grade/severity of encephalopathy.

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Article: Download PDF    DOI : https://www.doi.org/10.36106/gjra  

Cite This Article:

CORRELATION OF HYPONATREMIA WITH SEVERITY OF HEPATIC ENCEPHALOPATHY, Dr. Umakant Boke, Dr. Rahul G Vaidya GLOBAL JOURNAL FOR RESEARCH ANALYSIS : Volume-9 | Issue-6 | June-2020

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