Correlation Between Serum electrolytes and Fasting Blood Glucose with HbA1c In diabetic patients

Dr. Deepasha Shahi Bagzai; Dr. Prachi Paliwal; Dr. Darshana Jain; Dr. M.K.S. Shaikh

Volume : VII, Issue : XII, December - 2018

Correlation Between Serum electrolytes and Fasting Blood Glucose with HbA1c In diabetic patients

Dr. Deepasha Shahi Bagzai, Dr. Prachi Paliwal, Dr. Darshana Jain, Dr. M. K. S. Shaikh

Abstract :

Serum electrolytes play an important role in intermediary metabolism and cellular

function, including enzyme activities and electrical gradients. Alterations in serum electrolyte levels have been reported in diabetes mellitus. This electrolyte imbalance can in turn alter the course of the diabetes mellitus and its management. Through this study, we tried to understand the correlation between serum electrolytes like Sodium, Potassium & Magnesium with that of Fasting blood glucose & Glycosylated Hemoglobin in type 1 and type 2 Diabetes Mellitus.

MATERIALS & METHODS

Patients attending diabetic OPD at SAIMS medical college, Indore were randomly selected for any gender between the age group 16 to 70 years .A total 150 patients ( 50 type 1 diabetic & 100 type 2 diabetic , classified on the basis of ADA criteria ) were included in the study. Using different automated techniques, Fasting blood sugar ( FBS ),Glycosylated hemoglobin (HbA1c) and serum electrolytes were assessed after collecting blood samples.

RESULTS

In our study, a significant statistical difference (p<0.05) was observed when

HbA1c levels were correlated with serum sodium levels, both in type 1 as well

as type 2 diabetics . The association between Serum sodium and FBS was significant in type 2 diabetics only. When considering the whole study population together, Serum sodium levels were statistically significantly related with both FBS levels and HbA1c levels. The association of both Serum Potassium & Serum Magnesium with that of FBS and HbA1c levels was not significant.

CONCLUSION

FBS levels showed significant negative correlation with Serum Sodium in type 2 diabetics and Glycosylated hemoglobin showed significant negative correlation with Serum Sodium in diabetic patients, both type 1 and type 2. Serum Potassium and Serum Magnesium were not related with FBS or HbA1c levels.