COMPARSION OF THREE DIFFERENT DOSES OF Magnesium SULPHATE AS ADJUVANT TO BUPIVACAINE IN SPINAL ANAESTHESIA FOR ABDOMINAL HYSTRECTOMIES

Dr. Lokesh K Nety; Dr. Dilip Chandar; Dr. Sandeep Rathore; Dr. Gopal Maravi; Dr. R Mahindra

Volume : V, Issue : III, March - 2016

COMPARSION OF THREE DIFFERENT DOSES OF Magnesium SULPHATE AS ADJUVANT TO BUPIVACAINE IN SPINAL ANAESTHESIA FOR ABDOMINAL HYSTRECTOMIES

Dr. Lokesh K Nety, Dr. Dilip Chandar, Dr. Sandeep Rathore, Dr. Gopal Maravi, Dr. R Mahindra

Abstract :

Objectives: To compare three different doses of magnesium sulphate as adjuvant to bupivacaine in spinal anaesthesia for abdominal hystrectomies with respect to the duration of analgesia ,patient comfort and their side effects . Methods: 120 Patients of age between 35 to 55 years and of ASA I & II physical status who were planned to undergo abdominal hysterectomy in spinal anaesthesia. The study subjects were randomized into four groups consisting 30 patients and they were destined to receive the spinal drug with different concentrations of magnesium sulphate Results.Onset of motor block for group A was 5.35 � 0.51min , for group B was 5.28 � 0.48 min, for group C was 7.31 � 0.71min and for group D it was 7.8 � 0.76. Mean difference between groups were significant statistically (P<0.0001) except in group B where it is not significantly different. Mean duration of sensory block for group A was 129.4 � 7.86 min , for group B was 142.6 � 5.68 min , for group C it was 164.8 � 7.12 min and for group D it was 166 � 6.87 min. Mean difference between four groups were significant statistically (P<0.0001). Mean duration of analgesia for group A was 150.5 � 5.92 , for group B was 158.8 � 5.67 for group C was 188.8 � 8.8 min and in group D it was 190.5 � 5.14, the mean difference between four groups were significant statistically (P<0.0001). Conclusions Addition of 50, 75, or 100 mg magnesium sulfate 50% led to a significant delay in the onset of both sensory and motor blockade, and prolonged the duration of sensory and motor blockade without increasing major side effects