Comparison Of Neutrophil-Lymphocyte Ratio (NLR), Platelet Lymphocyte Ratio (PLR), And Mean Platelet Volume (MPV) In Preeclampsia And Normal Pregnancy

M. Iman Syahputra; Sarma N Lumbanraja; Deri Edianto; M Fidel Ganis Siregar; Melvin N.G. Barus; Riza Rivany

Volume : VIII, Issue : IV, April - 2019

Comparison Of Neutrophil-Lymphocyte Ratio (NLR), Platelet Lymphocyte Ratio (PLR), And Mean Platelet Volume (MPV) In Preeclampsia And Normal Pregnancy

M. Iman Syahputra, Sarma N Lumbanraja, Deri Edianto, M Fidel Ganis Siregar, Melvin N. G. Barus, Riza Rivany

Abstract :

Aim : To compare the value of NLR, PLR, and MPV in women with preeclampsia and normal pregnancy. Method : Analytic study with Case Control design, conducted in December 2018 at Adam Malik General Hospital Medan. Data of the patients who fulfilled the inclusion and exclusion criterias were obtained from medical record. Statistical analysis was performed and declared significant at p<0,05. 70 subjects with preeclampsia were obtained, with 70 subjects with normal pregnancy as control. Result : Median of NLR in normal pregnancy was 2,33 (min-max 0,77-6,64), median NLR in preeclampsia was 4,12 (min-max 1,81-16,50) with p = 0,001. Weak positive correlation was found between NLR and Systolic Blood Pressure of preeclampsia group at admission (p = 0,046, r = 0,239) and at discharge (p = 0,043, r = 0,242). No significant differences were found in PLR and MPV value between preeclampsia and normal pregnancy (p = 0,584 and 0,573). Conclusion : NLR value was significantly higher in preeclampsia compared to normal pregnancy. NLR also correlated with the increase of blood pressure in preeclampsia.