COMPARISION STUDY OF LIPID PROFILES IN BREAST CANCER PATIENTS AND HEALTHY CONTROL GROUP

Dr.Renu Meena; Dr.Shakuntala Saini

Volume : VIII, Issue : IX, September - 2019

COMPARISION STUDY OF LIPID PROFILES IN BREAST CANCER PATIENTS AND HEALTHY CONTROL GROUP

Dr. Renu Meena, Dr. Shakuntala Saini

Abstract :

Carcinoma of the east is the second commonest malignancy affecting half a million women worldwide each year. Epidemiological studies have revealed that 1 in 50 women in India can develop east cancer in their lifetime. A number of epidemiological studies have shown the increased risk of death from cancer with hypocholesterolaemia, although several studies proposed the low levels of cholesterol is a predisposing factor for carcinogenesis. So the present study was planned to investigate the alteration in the lipid profiles of patients with carcinoma of east in comparison with age matched control women. Aim: Estimate and compare Serum Lipid Profile for both in Breast cancer patients and normal individuals. Materials & Methods: Overnight Fasting blood samples of 156 Clinically diagnosed female cases of east cancer from OPD/IPD of Surgery and Oncology department And same number of normal individuals or control group has been taken from the OPD/IPD of Medicine Department and Emergency Department, S.M.S. Medical College and Hospital, Jaipur.Esmination of Serum Lipid Profiles Such as Total Cholesterol,HDL-Cholesterol, etc. were determine by enzymatic method in fully automated chemistry analyzer. Observation & Result: Mean�SD (mg/dl) for Serum TG level, in case of Breast Cancer Patients & Control Group were 202.74�53.45 and 178.77�99.36 respectively and p value was 0.008. Similarly, for Serum Cholesterol were 205.62�46.09 and 158.73�41.59 for Breast Cancer and Control group respectively.Also, p value of S.Cholesterol was 0.000. Mean and SD of S.HDL-Cholesterol level for both the groups were 39.20�5.30 and 40.46�8.96 respectively, p value was non significant. As far as S.LDL level was concert for Breast Cancer patients was 125.87�46.97 and for the control group was 81.54�29.21 and p value was 0.000. Level of S. VLDL were 40.55�10.69 and 35.70�19.49 for test group and control group respectively and p value was 0.008. Summary & Conclusion: Serum Cholesterol,Serum LDL was significantly lower in east cancer patients whereas Serum TG,VLDL was significantly higher in east cancer patients. Carcinoma east is commonest cancer in urban and rural females. Many women donot present themselves for check-up at hospitals or Medical because of varied reasons like illiteracy, monetary reasons and lack of knowledge. .Lots of efforts are needed both from the health systems as well as from local population for early diagnosis of cancer east