Comparative Study of different Doses of Oxytocin on patient undergoing Emergency Caesarean Section

Dr Swapan Kumar Rajak; Dr Santi Bhattacharya

Volume : VIII, Issue : V, May - 2019

Comparative Study of different Doses of Oxytocin on patient undergoing Emergency Caesarean Section

Dr Swapan Kumar Rajak, Dr Santi Bhattacharya

Abstract :

INTRODUCTION: During Caesarean Section oxytocin as an uterotonic agent is being administered routinely which causes contraction of uterus and it also causes certain adverse affects on patients if not given in proper dose.This Double Blinded study was designed to evaluate the response of different doses of oxytocin when used as an uterotonic agent during CS. Methods: 60 patients posted for emergency or elective Caesarean Section were divided into 2 groups of 30 each (Group G & Group S). Group G pts received 20 IU of oxytocin divided into 10IU IM & 10 IU IV, Group S pts received 10 IU of oxytocin 5 IM & 5 IV. They were randomly allocated to one of the groups by sealed envelope technique. All the pts were given 2 ml of 0.5% heavy Bupivacaine and were put on left lateral tilt. All the pts were preloaded with 1L of RL and no sedatives were used during the surgery. Vitals were noted prior to induction of pt and monitor containing BP, Chest leads, Sp02 was attached. Results: In group G- out of 30 patients receiving 20 IU of Oxytocin, 21 patients developed following symptoms (p=0.27): Conclusion: Oxytocin in its synthetic preparation contain Chlorbutanol as preservative which is the reason for its adverse affect when given in more than the prescribed doses, So oxytocin should be given in optimum dosage and if needed 20 IU should only be given to patients who are prone to develop post partum haemorrhage.