Comparative study of conventional local steroid injections only with multi-drugs therapy and steroid injections in Oral Submucosal Fibrosis (OSMF).

Dr. Bimal Kumar Mandal; Dr. Rina Das

Volume : VIII, Issue : VI, June - 2019

Comparative study of conventional local steroid injections only with multi-drugs therapy and steroid injections in Oral Submucosal Fibrosis (OSMF).

Dr. Bimal Kumar Mandal, Dr. Rina Das

Abstract :

Oral submucous fiosis (OSMF) is defined as the chronic inflammatory disease and progressive fiosis with localized collagen disorder involving oral mucosa. There are multiple pathophysiological changes that occur in this disease. The aim of this study is to establish that multidrugs needed for effective conservative treatment in oral submucous fiosis. A total number of 35 cases of OSMF managed in our ENT out patient department (OPD) over one year period ( March 2010 to Feuary 2011) were followed up until July 2011 and the results were analyzed retrospectively to find out any incidence of recurrence of this disease. All the cases received injection steroid and hyaluronidase with multivitamins (A,C and E in higher doses) for 10 weeks. At the end of treatment all the patients were relieved of burning sensation of mouth and got nearnormal mouth opening. The oral mucosa also changed from pale to pink. During follow-up no recurrence was detected. The study suggested that Vitamins A, C and E in higher doses are required to ensure best possible result apart from intralesional steroid and hyaluronidase as a standard conservative treatment protocol in oral submucous fiosis.