Comparative study of 5% imiquimod and 20% podophyllin in treatment of genital wart.

Dr Anil Mohite; Dr Pooja Prakash

Volume : V, Issue : V, May - 2016

Comparative study of 5% imiquimod and 20% podophyllin in treatment of genital wart.

Dr Anil Mohite, Dr Pooja Prakash

Abstract :

Genital wart cases are increasing in number due to lack of education, unprotected sex and higher rate of recurrence. Objectives: This is high time to analyze various treatments their efficacy and side effects. We are doing study to know the efficacy as well as side effect of podophyllin and imiquimod in treatment of genital wart. Study design, setting & participants: 60 patients fulfilling the inclusion and exclusion criteria were taken up for the study with attached proforma for risk factors was provided. Patients were segregated in to two groups and a longitudinal follow up study was done. Outcomes: In imiquimod (group A), total number of cured patients which had 100% clearance was 11 (39.28%) while total uncured patients which had less than 100% clearance were 17 (60.72%). In Group B (podophyllin), total number of cured patients which had 100% clearance was 17 (65.38%) while total uncured patients which had less than 100% clearance were 9 (34.62%). Conclusion: Our results conclude that for treatment of genital warts, Podophyllin is more efficacious than Imiquimod in terms of clearance but has higher rates of relapse and side effects.